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Pharmacology and Toxicology > Staff

Curriculum Vitae

Prof. Dr. rer. nat. Susanne Lutz

Prof. Dr. rer. nat. Susanne Lutz
Department of Pharmacology and Toxicology,
University Medical Center Goettingen,
Robert-Koch-Str. 40, 37075 Goettingen
Germany

Tel: +49 (0) 551 395699
Fax: +49 (0) 551 3910665
E-mail: susanne.lutz(at)med.uni-goettingen.de

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Academic Qualifications and Employment

Academic Qualifications and Employment  
2011 - Professor for Biochemical Pharmacology, Department of Pharmacology and Toxicology, University Medical Center Goettingen
2010 - Head of the "GPCR-signalling Research Unit“, Department of Pharmacology and Toxicology, University Medical Center Goettingen
2002 - 2010 Postdoctoral Fellow, Institute of Clinical and Experimental Pharmacology and Toxicology, Medical Faculty Mannheim, University of Heidelberg
08/2006 - 10/2006 Visiting Researcher, Life Sciences Institute, University of Michigan, USA
1997 - 2002 Graduate research assistant, Department of Cardiology, Faculty of Medicine, University of Heidelberg, Dr. rer. nat. received.
1996 - 1997 Graduate research assistant, Institute of Human Genetics, Faculty of Medicine, University of Heidelberg
1995 Diploma in Biology, University of Konstanz, Germany

Society Memberships

  • Member of the German Society of Pharmacology
  • Member of the German Society of Cardiology
  • Member of the International Society for Heart Research

Reviewer

  • Cardiovascular Research
  • Journal of Molecular and Cellular Cardiology
  • Naunyn-Schmiedeberg’s Archives of Pharmacology

Selected Publications

  • Wuertz CM, Lorincz A, Vettel C, Thomas MA, Wieland T, Lutz S. (2010) p63RhoGEF-a key mediator of angiotensin II- dependent signaling and processes in vascular smooth muscle cells. FASEB J.; 24(12): 4865-76. [PubMed]
  • Shankaranarayanan A, Boguth CA, Lutz S, Vettel C, Uhlemann F, Aittaleb M, Wieland T, Tesmer JJ. (2010) Galpha(q) allosterically activates and relieves autoinhibition of p63RhoGEF. Cell Signal.; 22(7): 1114-23. [PubMed]
  • Lutz S, Shankaranarayanan A, Coco C, Ridilla M, Nance MR, Vettel C, Baltus D, Evelyn CR, Neubig RR, Wieland T, Tesmer JJ. (2007) Structure of Gaq-p63RhoGEF-RhoA complex reveals a pathway for activation of RhoA by GPCRs. Science; 318(5858): 1923-7. [PubMed]
  • Williams S, Lutz S, Charlie N, Vettel C, Ailion M, Coco C, Tesmer JJG, Jorgensen E, Wieland T, Miller K. (2007) Trio’s Rho-specific GEF domain is the missing Gaq effector in the C. elegans synaptic signalling network. Genes Dev.; 21(21): 2731-46. [PubMed]
  • Lutz S, Freichel-Blomquist A, Yang Y, Ruemenapp U, Jakobs KH, Schmidt M, Wieland T. (2005) The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA. J Biol Chem.; 280(12): 11134-9. [PubMed]

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