Curriculum Vitae
Prof. Dr. med. Niels Voigt, FESC, FAHA
Prof. Dr. med. Niels Voigt
Department of Pharmacology and Toxicology,
University Medical Center Goettingen,
Robert-Koch-Str. 40, 37075 Goettingen
Germany
Tel: +49 (0) 551 3965174
Fax: +49 (0) 551 3965169
E-mail: niels.voigt(at)med.uni-goettingen.de
Research Interests
- Regulation of ion channels and calcium signaling in the normal and diseased heart
- Regulation of mitochondrial calcium-homeostasis in normal and diseased heart
- Development of cardiac arrhythmia models based on engineered heart muscle.
Education and Scientific Career
| Education and Scientific Career | |
|---|---|
| 2016 - | Professor for Molecular Pharmacology, Department of Pharmacology and Toxicology, University Medical Center Göttingen, University of Göttingen, Germany |
| 2012 - 2016 | Postdoctoral Scientist, Institute of Pharmacology, University of Duisburg-Essen, Germany |
| 2014 | Facultas Docendi & Venia Legendi (Senior Lecturer in Pharmacology and Toxicology) |
| 2013 | Board Certification in Pharmacology and Toxicology |
| 2010 - 2012 | Postdoctoral Scientist, Division of Experimental Cardiology, Medical Faculty Mannheim, Heidelberg University, Germany |
| 2008 - 2010 | Postdoctoral Scientist, Department of Pharmacology and Toxicology, Medical Faculty, Dresden University of Technology, Germany |
| 2007 | M.D. with merits (‘summa cum laude’) from the Medical Faculty "Carl Gustav Carus“, Dresden University of Technology, Germany |
| 2007 | Clinical examination and Graduation from Medical School |
| 2000 - 2007 | Medical School, Medical Faculty "Carl Gustav Carus“, Dresden University of Technology, Germany |
| 2003 - 2006 | Doctoral thesis at the Department of Pharmacology and Toxicology, Dresden University of Technology, Germany |
Experience at Research Institutes Abroad
- 2013: Laboratory of Dr. W. Jonathan Lederer, University of Maryland, Baltimore, USA
- 2008: Laboratory of Prof. Dr. David Eisner and Prof. Dr. Andrew Trafford, University of Manchester, Manchester, United Kingdom
- 2006: Laboratory of Prof. Dr. Stanley Nattel, Montreal Heart Institute, Montreal, Canada
Awards
- 2015: Teaching Award of the Medical Faculty of the University Duisburg-Essen 2015, Germany
- 2015: Oskar-Lapp-Award, German Cardiac Society, Germany
- 2013: Best of Basic Science Abstracts Award, American Heart Association Scientific Sessions 2013, Dallas, USA
- 2011: Poster Award, 35th Meeting of the European Working Group on Cardiac Cellular Electrophysiology, European Society of Cardiology, Oslo, Norway
- 2010: Highest Scoring Abstract Award from Germany, American Heart Association, Scientific Sessions 2010, Chicago, USA
- 2009: Woldemar Mobitz Award, German Cardiac Society, Germany
- 2009: Carl Gustav Carus Award for an outstanding dissertation, Medical Faculty, Dresden University of Technology, Germany
- 2004: Young Investigator Award 2004 (3rd Place), International Society for Heart Research (ISHR, European Section)
Editorial Boards
- Archives of Medical Science
- Basic Research in Cardiology
- Circulation: Genomic and Precision Medicine
- Journal of Molecular and Cellular Cardiology
- EP Europace
- Naunyn-Schmiedeberg’s Archives of Pharmacology
Reviewer for Scientific Journals
Basic Research in Cardiology, Biochimica et Biophysica Acta - Molecular Cell Research, BioMed Central (BMC) Research Notes, Cellular Physiology and Biochemistry, Circulation Arrhythmia and Electrophysiology, Clincal Epidemiology, European Journal of Pharmacology, Fundamental and Clinical Pharmacology, Frontiers in Pharmacology, Heart, Hypertension, International Journal of Cardiology, Journal of Cardiovascular Disease Research, Journal of Cardiovascular Pharmacology, Journal of Molecular and Cellular Cardiology, International Journal of Cardiology, Naunyn Schmiedeberg’s Archive of Pharmacology, Physiological Reports
Professional Memberships
- American Heart Association, Fellow (FAHA)
- Cardiac Electrophysiology Society (CES)
- Working Group on Cardiac Cellular Electrophysiology (EWGCCE), European Society of Cardiology (ESC)
- German Cardiac Society (DGK)
- German Society of Experimental and Clinical Pharmacology and Toxicology (DGPT)
- Heart Rhythm Society (HRS)
- European Society of Cardiology, Fellow (FESC)
Funding
- 2021 - 2024: Deutsches Zentrum für Herz-Kreislauf-Forschung e.V. (DZHK), DZHK-BHF-DHF Cooperation: “ “DNA damage in cytoskeletal protein mutation-induced Atrial Fibrillation: a guide to novel treatment and screening targets (DnAFiX)“ , Partnership Research Grant with Prof. Dr. Bianca J.J.M. Brundel, Amsterdam UMC, VUmc.
- Since 2020: Deutsches Zentrum für Herz-Kreislauf-Forschung e.V. (DZHK), Shared Expertise (SE181): ““Cellular electrophysiology and excitation-contraction coupling in atrial and ventricular cardiomyocytes“
- 2018 - 2024: Deutsche Forschungsgemeinschaft (DFG), Collaborative Research Center 1002 Project A13 (CRC1002 A13): “"Abnormal cytosolic calcium buffering and its role in atrial arrhythmogenesis in patients with heart failure"
- 2016 - 2022: Deutsche Forschungsgemeinschaft, International Research Training Group Project 12 (DFG IRTG1816 RP12): “Remodeling of human atrial cardiomyocytes in response to in-vitro tachypacing"
- since 2016: Deutsche Forschungsgemeinschaft (DFG VO 1568/3-1): “The role of atrial mitochondrial Ca2+-handling in arrhythmogenesis in patients with atrial fibrillation"
- 2016 - 2020: Else Kröner-Fresenius-Stiftung (EKFS 2016_A20): “Cellular basis for triggers and perpetuators of postoperative atrial fibrillation.”
Scientific Activities
| Scientific Activities | |
|---|---|
| since 2019 | American Heart Association, Council of Genomic and Precision Medicine, Early Career Committee Member |
| since 2018 | Chair of the Working Group on "Cellular Electrophysiology" (AG18) of the German Cardiac Society |
| 2016 - 2020 | Ex-officio board member of Council of Stroke, European Society of Cardiology |
| 2016 - 2018 | Vice-Chair of the Working Group on "Cellular Electrophysiology" (AG18) of the German Cardiac Society |
| 2016 - 2019 | Nucleus member of “Scientists of Tomorrow”, European Society of Cardiology |
| 2013-2017 | Nucleus member of the Working Group on "Myocardial Function and Energetics" (AG13) of the German Cardiac Society |
Selected Publications
Five most important
- Fakuade FE, Steckmeister V, Seibertz F, Gronwald J, Kestel S, Menzel J, Pronto JRD, Taha K, Haghighi F, Kensah G, Pearman CM, Wiedmann F, Teske AJ, Schmidt C, Dibb KM, El-Essawi A, Danner BC, Baraki H, Schwappach B, Kutschka I, Mason FE, Voigt N. (2020) Altered atrial cytosolic calcium handling contributes to the development of postoperative atrial fibrillation. Cardiovasc Res, doi: 10.1093/cvr/cvaa162. Cardiovasc Res, 117(7):1790-801. [PubMed]
- Voigt N, Heijman J, Wang Q, Chiang DY, Li N, Karck M, Wehrens XHT, Nattel S, Dobrev D. (2014) Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation. Circulation, 129 (2): 145-56. [PubMed]
- Voigt N, Li N, Wang Q, Wang W, Trafford AW, Abu-Taha I, Sun Q, Wieland T, Nattel S, Ravens U, Wehrens XHT, Dobrev D. (2012) Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation. Circulation, 125 (17): 2059-70. (Highlighted in Circulation’s “Most Read Articles in Arrhythmia and Electrophysiology”, Circulation 2013, 127: e509-19) [PubMed]
- Grandi E*, Pandit SV*, Voigt N*, Workman AJ, Dobrev D, Jalife J, Bers DM. (2011) Human atrial action potential and Ca2+ model: sinus rhythm and chronic atrial fibrillation. Circ Res, 109 (9): 1055-66. *Equal contribuation. [PubMed]
- Makary S*, Voigt N*, Maguy A*, Wakili R, Nishida K, Harada M, Dobrev D, Nattel S. (2011) Differential protein kinase C isoform regulation and increased constitutive activity of acetylcholine-regulated potassium channels in atrial remodeling. Circ Res, 109 (9): 1031-43. *Equal contribuation. [PubMed]
Book Chapters
- Nattel S, Heijman J, Voigt N, Wehrens XHT, Dobrev D (2017) The molecular pathophys-iology of atrial fibrillation. Cardiac Electrophysiology: From Cell to Bedside. Zipes D, Jalife J, Stevenson W (eds), 7th edition, Elsevier, pp. 396-408 ISBN: 978-0-3234-4733-1
- Dobrev D, Voigt N, Nattel S (2013) Cholinergic and constitutive regulation of atrial potassium channels. Cardiac Electrophysiology: From Cell to Bedside. Zipes D, Jalife J (eds), 6th edition, Elsevier, pp. 383-91. ISBN: 978-1-4556-2856-5
- Nattel S, Voigt N, Dobrev D (2013) Molecular pathophysiology of atrial fibrillation. Cardiac Electrophysiology: From Cell to Bedside. Zipes D, Jalife J (eds), 6th edition, Elsevier, pp. 449-58. ISBN: 978-1-4556-2856-5
For a complete list of publications, please access Scopus or PubMed.